Intragenomic enzyme complements

▶ The genomes of organisms exploited for biocatalysis are revealing families of enzymes that contribute to whole-cell activity. ▶ Functional analysis of these intragenomic complements reveals complementary activities. ▶ Intagenomic complements of ketoreductases, Baeyer-Villiger monooxygenases and hydrolases reveal diverse catalytic behaviour including substrate spectrum, enantioselectivity and thermostability.