کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10268984 | 459698 | 2011 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Electrochemical sensing the genotoxicity of Cu2O nanocubes activated by hydrogen peroxide electro-generated on the surface of Au nanoparticles
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی شیمی
مهندسی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Electrochemical sensing the genotoxicity of Cu2O nanocubes activated by hydrogen peroxide electro-generated on the surface of Au nanoparticles Electrochemical sensing the genotoxicity of Cu2O nanocubes activated by hydrogen peroxide electro-generated on the surface of Au nanoparticles](/preview/png/10268984.png)
چکیده انگلیسی
In order to investigate the genotoxicity of Cu2O nanocubes, a novel electrochemical biosensor was constructed by incorporating the mixture of Cu2O nanocubes and Au nanoparticles (AuNPs) into a multi-membrane containing natural ds-DNA. The ds-DNA was damaged in situ in the membrane and the DNA damage was monitored by DPV with two electrochemical indicators, Co(phen)33+ and Ru(NH3)63+. The mechanism studies showed that the nanoCu2O and AuNPs had synergistic effects on DNA damage and the DNA damage reagent (OH) was generated via electro-Fenton (E-Fenton) reactions on the surface of Cu2O nanocubes and Au nanoparticles. This method was very suitable to study the genotoxicity mechanisms of nanomaterials and it had potential application in studying some chemicals anti-oxidation property.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Electrochimica Acta - Volume 56, Issue 7, 28 February 2011, Pages 2828-2831
Journal: Electrochimica Acta - Volume 56, Issue 7, 28 February 2011, Pages 2828-2831
نویسندگان
Xueliang Wang, Kui Jiao, Guicun Li,