کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
103502 161383 2015 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Mitochondrial DNA control region sequences study in Saraiki population from Pakistan
ترجمه فارسی عنوان
مطالعه توالی های منطقه کنترل DNA میتوکندریایی در جمعیت سارایکی از پاکستان
کلمات کلیدی
DNA میتوکندریایی؛ مناطق قابل تصور؛ Haplotype؛ جمعیت سارایکی؛ پاکستان
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
چکیده انگلیسی

The analysis of mitochondrial DNA (mtDNA) control region was carried in 85 unrelated Sariki individuals living in the different provinces of Pakistan. DNA was extracted from blood preserved in EDTA vacutainers. Hypervariable regions (HV1, HV2 & HV3) were PCR amplified and sequenced. Sequencing results were aligned and compared with revised Cambridge reference sequence (rCRS). The sequencing results showed presence of total 63 different haplotypes, 58 of them are unique and 05 are common haplotypes shared by more than one individual. The most common haplotype observed was (W6) with a frequency 12.9% of population sample. The Saraiki population was detected with genetic diversity (0.9570) and power of discrimination (0.9458). This study will be beneficial for forensic casework.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Legal Medicine - Volume 17, Issue 2, March 2015, Pages 140–144
نویسندگان
, , , , , , , , , , ,