High-rate conversion of methane to methanol by Methylosinus trichosporium OB3b

► High-rate conversion of methane to methanol by Methylosinus trichosporium OB3b. ► Reactions are conducted at higher cell density in the presence of high concentrations of phosphate. ► More than 1.1 g/L methanol is produced in anaerobic bottles. ► A dense silicone tube membrane aerated bioreactor is applied to highly efficient and safe methane transformation to methanol.