Detection of benzo(a)pyrene photodegradation products using DNA electrochemical sensors

► We studied the interaction between photooxidised products of benzopirene and DNA using electrochemical sensor based on screen printed electrodes. ► The products are detectable using a ssDNA genomic sensor down to nanomolar range. ► Using oligonucleotides with amplified enzymatic detection, the products of photooxidation reaction form an adduct with the guanines and are able to inhibit the hybridisation reaction.