کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10436282 911067 2005 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Formation of high-resistance supported lipid bilayer on the surface of a silicon substrate with microelectrodes
موضوعات مرتبط
مهندسی و علوم پایه سایر رشته های مهندسی مهندسی پزشکی
پیش نمایش صفحه اول مقاله
Formation of high-resistance supported lipid bilayer on the surface of a silicon substrate with microelectrodes
چکیده انگلیسی
We have developed two basic technologies for fabrication of supported planar lipid bilayer membrane ion channel biosensors: a defect-free lipid bilayer formation on the substrate surface with electrode pores and a patterning technique for the hydrophobic self-assembled-monolayer to form the guard ring that reduces the lipid bilayer edge-leak current. The importance of the supported-membrane structure to achieve low noise and high-speed performance is suggested on the basis of the observed relation between the single-ion-channel current noise and the pore size.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Nanomedicine: Nanotechnology, Biology and Medicine - Volume 1, Issue 4, December 2005, Pages 317-322
نویسندگان
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