Association between adolescent emotional problems and metabolic syndrome: The modifying effect of C-reactive protein gene (CRP) polymorphisms

► Adolescent emotional problems are a risk factor for metabolic syndrome in mid life. ► CRP gene modifies the association. ► The association is stronger in CRP rs1205 CC homozygotes than in T allele carriers. ► CRP gene helps identifying depressed people at high risk for metabolic syndrome.