Capillary electrophoresis coupling with electrochemiluminescence detection: a review

The development of electrochemiluminescence (ECL) detection for capillary electrophoresis (CE) is critically reviewed. After a simple discussion of the mechanism of ECL concerning in CE-ECL system and CE mode, special attention is focused on the instrumental design, mainly including addition of reagent, field decoupler, and ECL efficiency. Application of the CE-ECL technique was also given.