An NMR-based metabolomic assessment of cultured cobia health in response to dietary manipulation

► NMR-based metabolomics is shown to be a useful tool in aquaculture. ► Cobia fed reduced fishmeal diets were metabolically different than controls. ► Elevated tyrosine in cobia on reduced fishmeal diets may signify thyroid disruption. ► High lactate in cobia fed a formulated control diet may reflect enhanced LAB activity.