The ameliorating effect of Filipendula hexapetala extracts on hepatorenal toxicity of cisplatin

- HPLC analysis of Filipendula hexapetala aerial part and root methanolic extracts was performed.
- Wistar rats were treated with the F. hexapetala extracts and cisplatin.
- F. hexapetala extracts ameliorated cisplatin-induced nephro- and hepatotoxicity in vivo.
- The extracts in lower concentrations (100 mg/kg b.w.) showed antigenotoxic effect.