Synthesis, characterization, and cytotoxicities of platinum(II) complexes bearing pyridinecarboxaldimines containing bulky aromatic groups

Six platinum dichloride pyridinecarboxaldimine complexes containing bulky aryl groups have been prepared and characterized fully. Cytotoxicities of the complexes have been investigated against OV2008 (human ovarian carcinoma) and the analogous cisplatin-resistant cell line C13.