Synthesis, DNA binding, photo-induced DNA cleavage, cytotoxicity and apoptosis studies of copper(II) complexes

Copper(II) complexes with planar heterocyclic bases are prepared. The DNA cleavage experiments show singlet oxygen as the reactive species. The cytotoxicity of the complexes against HeLa cancer cell evaluated and the HeLa cell died through an apoptosis process induced by complexes which indicates that the complexes 1 and 2 are promising drugs for cancer.