Design and synthesis of a novel 2-oxindole scaffold as a highly potent and brain-penetrant phosphodiesterase 10A inhibitor

Design and synthesis of a novel 2-oxindole scaffold as a highly potent and brain-penetrant phosphodiesterase 10A inhibitor

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry - Volume 23, Issue 22, 15 November 2015, Pages 7138-7149

Masato Yoshikawa, Haruhi Kamisaki, Jun Kunitomo, Hideyuki Oki, Hironori Kokubo, Akihiro Suzuki, Tomomi Ikemoto, Kosuke Nakashima, Naomi Kamiguchi, Akina Harada, Haruhide Kimura, Takahiko Taniguchi,