Synthesis and β-glucuronidase inhibitory activity of 2-arylquinazolin-4(3H)-ones

Twenty-five 2-arylquinazolin-4(3H)-one derivatives 1-25 were synthesized by reacting anthranilamide with various benzaldehydes using CuCl2·2H2O as a catalyst in ethanol under reflux for 16 h. Synthetic 2-arylquinazolin-4(3H) ones 1-25 were evaluated for their β-glucuronidase inhibitory potential.