کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10588567 981474 2010 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Structure-activity relationships of mononuclear metal-thiosemicarbazone complexes endowed with potent antiplasmodial and antiamoebic activities
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Structure-activity relationships of mononuclear metal-thiosemicarbazone complexes endowed with potent antiplasmodial and antiamoebic activities
چکیده انگلیسی
Antiparasitic metals: a set of promising metal-based antiprotozoal agents were explored. As a result, structure-activity relationships data were collected and steps were made towards identification of new antiplasmodium (NT1Cu, IC50 = 4.6 μM) and antiamoebic (NT2Pd, IC50 = 0.6 μM) prototypes, which are able to reduce the proliferation of these parasites at concentrations that are not cytotoxic to mammalian cells.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry - Volume 18, Issue 18, 15 September 2010, Pages 6857-6864
نویسندگان
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