کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10588759 981485 2011 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
CoMFA and CoMSIA studies on 5-hydroxyindole-3-carboxylate derivatives as 5-lipoxygenase inhibitors: Generation of homology model and docking studies
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
CoMFA and CoMSIA studies on 5-hydroxyindole-3-carboxylate derivatives as 5-lipoxygenase inhibitors: Generation of homology model and docking studies
چکیده انگلیسی
In this Letter, CoMFA and CoMSIA were performed on a series of 2-substituted 5-hydroxyindole-3-carboxylate derivatives as potent 5-LOX inhibitors. The data generated from the present study will further help design and validate novel and potent 5-LOX inhibitors.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 21, Issue 1, 1 January 2011, Pages 456-462
نویسندگان
, , , ,