Box-Behnken design based statistical modeling for ultrasound-assisted extraction of corn silk polysaccharide

► UAE of polysaccharide from corn silk. ► Box-Behnken design was applied to find out the optimum conditions. ► Second order polynomial regression models were developed. ► Optimal conditions were determined by Derringer's desired function methodology. ► Experimental values showed good agreement with the values predicted by the model.