Electrospun anti-adhesion barrier made of chitosan alginate for reducing peritoneal adhesions

► Chitosan alginate was electrospun into fibrous mat for tissue anti-adhesion. ► Disintegration of resulting mats in DMEM was slower than calcium alginate by 36%. ► Chitosan alginate mat exhibited non-cytotoxicity and induced apoptosis in vitro. ► The in vivo adhesion score was 40% for rats treated with chitosan alginate mats.