Structural characterisation of oligosaccharides obtained by Fenton-type radical depolymerisation of dermatan sulfate

► All structures in low molecular weight heparins and other GAGs must be characterised. ► NMR analysis of the Fenton-type radical depolymerisation of dermatansulfate reported. ► Native DS sequences containing almost exclusively GalNAc as the reducing sugar observed. ► Non-native C-4 sulfated N-acetylgalactosaminic acid in place of the reducing GalNAc4S present. ► Hetercorrelated NMR methods at 800 MHz capable of analysing mixtures of related oligosaccharides.