Bi- and trivalent glycopeptide mannopyranosides as inhibitors of type 1 fimbriae-mediated bacterial adhesion: variation of valency, aglycon and scaffolding

Mannopyranoside ligands for the bacterial lectin FimH with diverse aglycon moieties can be scaffolded on small peptides in order to vary the valency of the resulting glycopeptides, and the spatial arrangement of the ligated saccharides.