کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10609866 | 984736 | 2011 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Copolymers of ethyl glycolate and Ï-pentadecalactone: Enzymatic synthesis and solid-state characterization
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Synthesis of poly(PDL-GA) copolymers is successfully achieved via enzymatic catalysis starting from Ï-pentadecalactone and ethyl glycolate. In the copolymers PDL and GA units show a significant tendency to an alternating arrangement. All copolyesters display a high degree of crystallinity (Ïc â 70%) regardless of their composition (GA content: 0-27 mol%). Analysis of melting point depression by the Wendling-Suter model suggests inclusion of GA units in PPDL-type crystals. Accordingly WAXS results show that, with increasing GA unit content, the PPDL unit cell undergoes a gradual increase of c-axis (chain axis) periodicity, compatible with the insertion of GA units within the crystallizing PDL sequences. Poly(PDL-GA) copolymers combine typically hydrophobic (PDL) and hydrophilic (GA) monomers and are promising new tuneable drug-delivery systems for medical applications. In this perspective, poly(PDL-GA) nanoparticles are fabricated and characterized.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Polymer Journal - Volume 47, Issue 5, May 2011, Pages 942-948
Journal: European Polymer Journal - Volume 47, Issue 5, May 2011, Pages 942-948
نویسندگان
Laura Mazzocchetti, Mariastella Scandola, Zhaozhong Jiang,