کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10691045 | 1019580 | 2016 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Carotid Atherosclerotic Plaque Alters the Direction of Longitudinal Motion in the Artery Wall
ترجمه فارسی عنوان
پلاک آترواسکلروتیک کاروتید باعث تغییر جهت حرکت طولی در دیواره شریان می شود
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
فیزیک و نجوم
آکوستیک و فرا صوت
چکیده انگلیسی
Longitudinal motion of the artery, a cyclical, bidirectional movement of the wall in the long axis of the artery, has recently gained interest in the characterization of artery function. The aim of this study was to evaluate longitudinal motion in patients with internal carotid atherosclerotic plaques. Speckle tracking ultrasound was used to assess common carotid artery wall motion in 12 patients with carotid plaque causing either moderate (50%-79%) or severe (80%-99%) stenosis based on the North American Carotid Endarterectomy Trial, and 23 healthy participants. Although healthy individuals were found to have a retrograde wall motion pattern, a distinct anterograde pattern was noted with plaque presence. Importantly, patients with severe plaque stenosis had greater anterograde motion (0.53 ± 0.36 mm) than those with moderate stenosis (0.17 ± 0.15 mm) (p < 0.05), likely owing to high wall shear stresses associated with greater peak systolic velocities at the site of stenosis (severe: 342.0 ± 99.4 cm/s, moderate: 177.5 ± 31.2 cm/s, p < 0.01). There were no differences in peak systolic velocities at plaque-free segments between plaque groups (severe: 80.2 ± 24.8 cm/s, moderate: 92.7 ± 23.0 cm/s). Blood flow at stenotic areas better predicted motion than plaque-free segments. We conclude that the presence of carotid plaque can have significant influence on longitudinal motion, with significantly greater anterograde displacements with increased stenosis. Future studies are needed to further investigate carotid artery wall mechanics.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Ultrasound in Medicine & Biology - Volume 42, Issue 9, September 2016, Pages 2114-2122
Journal: Ultrasound in Medicine & Biology - Volume 42, Issue 9, September 2016, Pages 2114-2122
نویسندگان
Jimmy Tat, Ioannis N. Psaromiligkos, Stella S. Daskalopoulou,