کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10691273 | 1019591 | 2015 | 16 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Visualizing the Stress Distribution Within Vascular Tissues Using Intravascular Ultrasound Elastography: A Preliminary Investigation
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
فیزیک و نجوم
آکوستیک و فرا صوت
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![عکس صفحه اول مقاله: Visualizing the Stress Distribution Within Vascular Tissues Using Intravascular Ultrasound Elastography: A Preliminary Investigation Visualizing the Stress Distribution Within Vascular Tissues Using Intravascular Ultrasound Elastography: A Preliminary Investigation](/preview/png/10691273.png)
چکیده انگلیسی
A methodology for computing the stress distribution of vascular tissue using finite element-based, intravascular ultrasound (IVUS) reconstruction elastography is described. This information could help cardiologists detect life-threatening atherosclerotic plaques and predict their propensity to rupture. The calculation of vessel stresses requires the measurement of strain from the ultrasound images, a calibrating pressure measurement and additional model assumptions. In this work, we conducted simulation studies to investigate the effect of varying the model assumptions, specifically Poisson's ratio and the outer boundary conditions, on the resulting stress fields. In both simulation and phantom studies, we created vessel geometries with two fibrous cap thicknesses to determine if we could detect a difference in peak stress (spatially) between the two. The results revealed that (i) Poisson's ratios had negligible impact on the accuracy of stress elastograms, (ii) the outer boundary condition assumption had the greatest effect on the resulting modulus and stress distributions and (iii) in simulation and in phantom experiments, our stress imaging technique was able to detect an increased peak stress for the vessel geometry with the smaller cap thickness. This work is a first step toward understanding and creating a robust stress measurement technique for evaluating atherosclerotic plaques using IVUS elastography.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Ultrasound in Medicine & Biology - Volume 41, Issue 6, June 2015, Pages 1616-1631
Journal: Ultrasound in Medicine & Biology - Volume 41, Issue 6, June 2015, Pages 1616-1631
نویسندگان
Michael S. Richards, Renato Perucchio, Marvin M. Doyley,