کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10691867 | 1019612 | 2013 | 12 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The Early Phases of Bone Healing Can Be Differentiated in a Rat Osteotomy Model by Focused Transverse-Transmission Ultrasound
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کلمات کلیدی
Osteotomy - استئوتومیBone - استخوان Fracture healing - التیام شکستگیMicro-computed tomography - توموگرافی کامپیوتری میکروspeed of sound - سرعت صوتQuantitative ultrasound - سونوگرافی کمbroadband ultrasound attenuation - ضعیف التراسوند باند پهنSmall animal model - مدل حیوان کوچکEndochondral ossification - پوکی استخوان اندوخوردار
موضوعات مرتبط
مهندسی و علوم پایه
فیزیک و نجوم
آکوستیک و فرا صوت
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Here we describe the use of a 5-MHz focused transmission system to image the bone repair region and to distinguish the early healing phases in a rat osteotomy (OT) model. Twelve-month-old female rats underwent a 2-mm OT. After 6 wk of consolidation, 2-D projection images of time-of-flight, speed of sound, and ultrasound attenuation were measured in vitro. The tissue types in the OT gap region were assessed by site-matched histology sections and micro-computed tomography (μCT). In the cases investigated, OT gap regions containing fibrous tissue (group A) were found to have similar properties compared with adjacent muscle tissue, whereas regions filled with cartilage and mineralized callus tissues (group B) differed significantly. Analysis of variance revealed that the healing group had a stronger effect on acoustic parameters (F < 35) than on μCT-based parameters (F < 22). This pilot study reports the feasibility of transverse transmission quantitative ultrasound in assessment of the onset of cartilage formation during callus formation.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Ultrasound in Medicine & Biology - Volume 39, Issue 9, September 2013, Pages 1642-1653
Journal: Ultrasound in Medicine & Biology - Volume 39, Issue 9, September 2013, Pages 1642-1653
نویسندگان
Daniel Rohrbach, Bernd Preininger, Bernhard Hesse, Hinnerk Gerigk, Carsten Perka, Kay Raum,