کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10693226 | 1019762 | 2005 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The effect of size on the acoustic response of polymer-shelled contrast agents
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
فیزیک و نجوم
آکوستیک و فرا صوت
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چکیده انگلیسی
In this technical note, we study three polymer-shelled microbubble contrast agents manufactured by POINT Biomedical Corporation that have identical shell composition and mean volumetric diameters of 0.74 μm, 0.91 μm and 1.33 μm. We investigate the effect of agent size on the amplitude, frequency and probability of acoustic echoes received in response to five-cycle, 2.25-MHz pulses of varying pressure. We find that the amplitude and frequency response from the three agents is not significantly different. However, significant differences among the agents do exist in the probability of response to acoustic interrogation: at a pressure of 1.06 MPa, an echo from the 1.33 μm agent is 5 times as likely as an echo from the 0.91 μm agent and 18 times as likely as an echo from the 0.74 μm agent. We hypothesize that there exists an effective pressure-dependent threshold diameter above which single polymer-shelled agents respond to acoustic interrogation. (E-mail: erwisner@ucdavis.edu)
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Ultrasound in Medicine & Biology - Volume 31, Issue 3, March 2005, Pages 439-444
Journal: Ultrasound in Medicine & Biology - Volume 31, Issue 3, March 2005, Pages 439-444
نویسندگان
Susannah H. Bloch, Robert E. Short, Katherine W. Ferrara, Erik R. Wisner,