Mechanisms underlying mouse TNF-α stimulated neutrophil derived microparticle generation

- TNF-α treatment generates Neutrophil Derived Microparticles (NDMPs).
- Activation of either TNFr1 or TNFr2 is sufficient for NDMP generation.
- TNFr1 activation generates NDMPs through Caspase 8.
- TNFr1 and TNFr2 generate NDMPs through NF-κB.