5-Aza-dC treatment induces mesenchymal-to-epithelial transition in 1st trimester trophoblast cell line HTR8/SVneo

► Distinct DNA methylation between cytotrophoblast and extravillous trophoblast. ► 5-Aza-dC treatment increases epithelial gene expression in HTR8/SVneo cells. ► 5-Aza-dC treatment causes mesenchymal to epithelial transition.