Angiogenesis therapy for brain infarction using a slow-releasing drug delivery system for fibroblast growth factor 2

► FGF2 apatite coating can prevent infarction of the penumbra by the angiogenesis. ► FGF2 apatite coating is expected to be a useful material for brain infarction. ► FGF2 apatite coating continues to release FGF2 over 16 days.