Simvastatin inhibits ox-LDL-induced inflammatory adipokines secretion via amelioration of ER stress in 3T3-L1 adipocyte

► Ox-LDL triggered ER stress in differentiated 3T3-L1 adipocytes. ► Ox-LDL increased inflammatory adipokines through activation of ER stress. ► Simvastatin suppressed the ox-LDL-induced ER stress in 3T3-L1 adipocytes. ► Simvastatin reduced inflammatory adipokines through amelioration of ER stress.