Chloroquine enhances cobalt chloride-induced leukemic cell differentiation via the suppression of autophagy at the late phase

► CQ potentiates CoCl2-induced growth arrest and differentiation of leukemic cells. ► CQ increases CoCl2-induced HIF-1 α accumulation. ► Suppression of LAMP1 and LAMP2 expression enhances CoCl2-induced differentiation. ► Interference of Beclin-1 expression does not affect CoCl2-induced differentiation.