Keywords: BBB; blood-brain barrier; OGD; Oxygen Glucose Deprevation; SGLT6; sodium dependent myo-inositol transporter; SMIT1; sodium myo-inositol transporter 1; DCI; d-chiro-inositol; AQP4; Aquaporin Transport 4; GFAP; Glial fibrillary acidic protein; HMIT; H+depen
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Keywords: Aβ; amyloid-β; APP; amyloid precursor protein; APP-CTF; APP-carboxy-terminal fragment; β-CTF; amyloid precursor protein β-carboxy-terminal fragment; BSA; bovine serum albumin; CQ; chloroquine; DMEM; Dulbecco's modified Eagle's medium; DPBS; Dulbecco's
Keywords: Atg; autophagy related; BafA; Bafilomycin A1; CrispR; clustered regularly interspaced short palindromic repeats; EBSS; Earle's balanced salt solution; HTS; high-throughput screen; LIR; LC3-interacting region; MAD; median absolute deviation; PE; phosphat
Keywords: AG; aminoguanidine; CAA; complete amino acids; DMEM; Dulbecco's Modified Eagle's Medium; EBSS; Earle's Balanced Salt Solution; LC3; microtubule-associated protein 1 light chain 3; LC3-IIs; cytosolic (soluble) form of LC3-II; l-NMMA; NG-monomethyl-l-
Keywords: ATG; Autophagy-related gene; EBSS; Earle's balanced salt solution; EGFP-LC3; Enhanced green fluorescent protein-microtubule-associated protein-1 light chain 3; MDC; Monodansylcadaverine; mTOR; Mammalian target of rapamycin; WS; Werner syndrome; WRNp; Wern
Keywords: AFLD; alcoholic fatty liver disease; ALT; alanine aminotransferase; CBZ; carbamazepine; CQ; chloroquine; EBSS; Earle's Balanced Salt Solution; HFD; high fat diet; LD; lipid droplets; NAFLD; non-alcoholic fatty liver disease; RP; rapamycin; TG; triglycer
Keywords: CoCl2; cobalt chloride; AML; acute myeloid leukemia; HIF-1 α; hypoxia-inducible factor-1 α; CQ; chloroquine; LAMP1 and 2; lysosome-associated membrane proteins 1 and 2; APL; acute promyelocytic leukemia; ATRA; all-trans retinoic acid; ATO; arsenic triox
The reduction of l-cystine to l-cysteine in the supernatant of A549 cell culture causes imipenem inactivation
Keywords: l-Cysteine; l-Cystine; A549; Carbapenems; Imipenem; Inactivation; CPs; carbapenes; FCS; fetal calf serum; RPMI; FCS free RPMI 1640 medium; Cys; l-cysteine; CS; l-cystine; IPM; imipenem; EBSS; Earle's balanced salt solution; AA-EBSS; EBSS supplemented with
Hepatitis B Virus X protein elevates Parkin-mediated mitophagy through Lon Peptidase in starvation
Keywords: HCC; Hepatocellular Carcinoma; HBV; Hepatitis B virus; HBx; Hepatitis B Virus X protein; PINK1; PTEN Induced Putative Kinase 1; UPRmt; Mitochondrial Unfolded-Protein Response; LONP1; Lon Peptidase 1; EBSS; Earle's balance salt solution; LC3; microtubule-a
GLA supplementation regulates PHD2 mediated hypoxia and mitochondrial apoptosis in DMBA induced mammary gland carcinoma
Keywords: AA; arachidonic acid; AB; alveolar bud; AAA; aromatic amino acid; BCAA; branched chain amino acid; BSA; bovine serum albumin; BMRB; biological magnetic resonance databank; CEC; cuboidal epithelial cell; CPMG; carr-purcell-meiboom-gill; DMBA; 7, 12-d
Morusin induces paraptosis-like cell death through mitochondrial calcium overload and dysfunction in epithelial ovarian cancer
Keywords: Morusin; Paraptosis-like cell death; EOC; VDAC; Mitochondrial Ca2+ overload; Mitochondrial dysfunction; EOC; epithelial ovarian cancer; VDAC; voltage-dependent anion channel; DIDS; 4, 4â²-diisothiocyanostilbene-2, 2â²-disulfonic acid; NAC; N-acetyl-l-cy
ATG4B inhibitor FMK-9a induces autophagy independent on its enzyme inhibition
Keywords: Atg4B; Autophagy; Delipidation; FMK-9a; FRET assay; Atg4B; autophagy-related 4B; Baf; bafilomycin A1; CM; complete medium; CQ; chloroquine; EBSS; Earle's Balanced Salt Solution; FMK; fluoromethylketone; FRET; fluorescence resonance energy transfer; GABARA
Monitoring autophagic flux using p62/SQSTM1 based luciferase reporters in glioma cells
Keywords: 3-MA; 3-methyladenine; CQ; Chloroquine; Rapa; Rapamycin; EBSS; Dulbecco's Phosphate-Buffered Saline; ATG5; Autophagy-related 5; MAP1LC3/LC3; Microtubule-associated protein 1 light chain 3; mTOR; Mammalian (or mechanistic) Target of Rapamycin; SQSTM1; sequ
Balasubramide derivative 3C modulates microglia activation via CaMKKβ-dependent AMPK/PGC-1α pathway in neuroinflammatory conditions
Keywords: AMPK; AMP-activated protein kinase; CaMKKβ; calcium/calmodulin-dependent protein kinase kinase beta; CBF; cerebral blood flow; CCA; common carotid artery; EBSS; glucose-free Earle's balanced salt solution; ECA; external carotid artery; ELISA; cytokine en
Autophagy as a pharmacological target in hematopoiesis and hematological disorders
Keywords: 3-MA; 3-methyladenine; ALL; acute lymphoblastic leukemia; AMKL; acute megakaryoblastic leukemia; AML; acute myeloid leukemia; AMPK; 5â²-adenosine monophosphate-activated protein kinase; APL; acute promyelocytic leukemia; Atg; autophagy-related proteins;
Indian propolis ameliorates the mitomycin C-induced testicular toxicity by reducing DNA damage and elevating the antioxidant activity
Keywords: HEIP; hydroethanolic extract of Indian propolis; MMC; mitomycin C; PBS; phosphate buffer saline; GSH; glutathione; SOD; superoxide dismutase; CAT; catalase; EBSS; Earles balanced salt solution; CMA3; chromomycin A3; SCD; sperm chromatin dispersion test; N
Understanding the influence of HEPES buffer concentration on the biodegradation of pure magnesium: An electrochemical study
Keywords: Magnesium; Biomaterials; Degradation; HEPES; EBSS;
The replacement of the 2-methoxy substituent of N-((6,6-diphenyl-1,4-dioxan-2-yl)methyl)-2-(2-methoxyphenoxy)ethan-1-amine improves the selectivity for 5-HT1A receptor over α1-adrenoceptor and D2-like receptor subtypes
Keywords: 5-HT1A receptor; α1-Adrenoceptor subtypes; D2-like receptor subtypes; Selective 5-HT1A receptor agonists; Docking studies; Anxiolytic effect; 5-HT; 5-hydroxytriptamine; GPCR; G protein-coupled receptor; TM; transmembrane; ARs; adrenoceptors; SAR; structu
Original ArticleOsteopontin induces autophagy to promote chemo-resistance in human hepatocellular carcinoma cells
Keywords: Osteopontin; Autophagy; FoxO3a; Chemo-resistance; Stem-like phenotype; OPN; osteopontin; HCC; hepatocellular carcinoma; EBSS; Earle's Balanced Salt Solution medium; BafA1; Bafilomycin A1; CM; condition medium; LC3; microtubule-associated protein 1 light c
Autophagic lysosomal reformation depends on mTOR reactivation in H2O2-induced autophagy
Keywords: ALR; autophagic lysosomal reformation; H2O2; hydrogen peroxide; Rab7; Ras-related protein 7; PI4P; phosphatidylinositol 4-phosphate; mTOR; mammalian mechanistic target of rapamycin; Atg; autophagy-related gene; DMEM; Dulbecco's Modified Eagle's Medium; EB
Telomerase reverse transcriptase induces basal and amino acid starvation-induced autophagy through mTORC1
Keywords: Autophagy; Cell viability; Human telomerase reverse transcriptase (hTERT); Mammalian target of rapamycin complex 1 (mTORC1); Telomerase; AMPK; AMP-activated protein kinase; DMEM; Dulbecco's Modified Eagle's medium; EBSS; Earle's balanced salt solution; ER
Trans-Golgi protein p230/golgin-245 is involved in phagophore formation
Keywords: AP2; adaptor-protein 2; EBSS; Earle's balanced salt solution; ER; endoplasmic reticulum; KD; knock-down; MACF1; microtubule actin crosslinking protein 1; LC3; microtubule-associated protein 1 light chain 3; PM; plasma membrane; TGN; trans-Golgi network;
Non-animal photosafety screening for complex cosmetic ingredients with photochemical and photobiochemical assessment tools
Keywords: 3T3 NRU PT; 3T3 neutral red uptake phototoxicity testing; DMSO; dimethyl sulfoxide; EBSS; Earle's balanced salt solution; ECVAM; European Centre for Validation of Alternative Methods; ICH; International Conference on Harmonization of Technical Requireme
Autophagic flux determination in vivo and ex vivo
Keywords: ATP; adenosine triphosphate; BBB; blood brain barrier; BRB; blood retinal barrier; BGT; BSA/glycine/Triton X-100; BSA; bovine serum albumin; CNS; central nervous system; DABCO; 1,4-diazabicyclo[2.2.2]octane; DAPI; 4,6-diamidino-2-phenylindole dihydrochlor
Guttiferone K induces autophagy and sensitizes cancer cells to nutrient stress-induced cell death
Keywords: Apoptosis; Autophagy; Guttiferone K; Natural compound; Starvation; BAFA1; bafilomycin A1; DCFH-DA; dichlorofluorescin diacetate; DMEM; Dulbecco's modification of Eagle's medium; EBSS; Earle's balanced salt solution; GUTK; Guttiferone K; HCQ; hydroxychloro
Functional characterization of the organic cation transporters (OCTs) in human airway pulmonary epithelial cells
Keywords: ALI; air-liquid interface culture; EBSS; Earle's Balanced Salt Solution; MPP+; 1-methyl-4-phenylpyridinium; OCT; organic cation transporter; PBS; phosphate-buffered saline solution; PGE2; prostaglandine E2; TEER; transepithelial electrical resistance; P
Integrated and comparative miRNA analysis of starvation-induced autophagy in mouse embryonic fibroblasts
Keywords: AMPK; AMP-activated protein kinase; ATG; AuTophaGy related; CQ; chloroquine; EBSS; Earle's balanced salt solution; FBS; fetal bovine serum; FIP200; focal adhesion kinase (FAK) family interacting protein of 200Â kDa; LC3; microtubule-associated protein 1 l
Genistein modulation of streptozotocin diabetes in male B6C3F1 mice can be induced by diet
Keywords: BGL; blood glucose levels; EBSS; Earle's Balanced Salt Solution; GE; genistein; HFD; high fat diet; NK cells; natural killer cells; NOD; non-obese diabetic; NTP; NTP-2000 open formula; SOF; soy- and alfalfa-free 5K96 verified casein feed; STZ; streptozoto
CCCP-Induced LC3 lipidation depends on Atg9 whereas FIP200/Atg13 and Beclin 1/Atg14 are dispensable
Keywords: CCCP; carbonyl cyanide m-chlorophenylhydrazone; CQ; chloroquine; EBSS; earle's balanced salt solution; LC3; microtube-associated protein light chain 3; MEFs; mouse embryonic fibroblasts; UKC; ULK kinase complex; Autophagy; CCCP; Atg9; Beclin 1; FIP200;
Differential regulation of fibrinogen γ chain splice isoforms by interleukin-6
Keywords: ANOVA; analysis of variance; BSA; bovine serum albumin; CRP; C-reactive protein; EBSS; Earle's balanced salt solution; ELISA; enzyme-linked immunosorbant assay; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; HRP; horseradish peroxidase; IL-1β; interleu
Phospholipase C-related catalytically inactive protein, a novel microtubule-associated protein 1 light chain 3-binding protein, negatively regulates autophagosome formation
Keywords: a.a.; amino acid residues; DMEM; Dulbecco's modified Eagle's medium; EBSS; Earle's balanced salt solution; GABARAP; GABAA receptor-associated protein; GFP; green fluorescent protein; GFP-LC3 WT; GFP-LC3-expressing WT; GST; glutathione S-transferase;
Identification of the factors responsible for the in vitro pro-oxidant and cytotoxic activities of the olive polyphenols oleuropein and hydroxytyrosol
Keywords: Amplex® Red reagent; 10-acetyl-3,7-dihydroxyphenoxazine; DMEM/F12; Dulbecco's modified Eagle medium-F12 mixture; EBSS; earle's balanced salt solution; FBS; fetal bovine serum; FOX; ferrous oxidation-xylenol orange; H2O2; hydrogen peroxide; MEM; minim
Arsenic trioxide (As2O3) induces apoptosis and necrosis mediated cell death through mitochondrial membrane potential damage and elevated production of reactive oxygen species in PLHC-1 fish cell line
Keywords: MTT; (3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; IC50; inhibitory concentration; FACS; fluorescence-activated cell sorter; FITC/PI; fluorescein isothiocyanate propidium iodide; JC-1 dye; 5,5â²,6,6â²-tetrachloro-1,1â²,3,3â²-tetraethy
Synthesis and biological evaluation of 18F-labeled fluoropropyl tryptophan analogs as potential PET probes for tumor imaging
Keywords: Amino acids; Tryptophan; Tumor imaging; PET; LAT; aadc; aromatic amino acid decarboxylase; APUD; amine precursor uptake and decarboxylation; BCH; 2-amino-2-norbornanecarboxylic acid; BF3·Et2O; boron trifluoride etherate; [11C]5HTP; 5-hydroxy-l-[β-11C]tr
Impedance measurement for real time detection of neuronal cell death
Keywords: bFGF; basic fibroblast growth factor; CAF; cytosine β-d-arabinofuranoside; Clti; cell index at a given time point; DMEM; Dulbecco's minimal essential medium; DMSO; dimethyl sulfoxide; EBSS; Earlés balanced salt solution; EGF; epidermal growth factor; FC
HOCl causes necrotic cell death in human monocyte derived macrophages through calcium dependent calpain activation
Keywords: ÎΨm; mitochondrial membrane potential; A23187; 4-bromo-calcium ionophore A23187; ANT; adenine nucleotide translocator; EBSS; Earle's balanced salt solution; fluo-3-AM ester; fluo-3-acetoxymethyl ester; HEPES; 4-(2-hydroxyethyl)-1-piperazineethanesulfoni
Valproic acid induces the glutamate transporter excitatory amino acid transporter-3 in human oligodendroglioma cells
Keywords: DHK; dihydrokainate; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; DTT; 1,4-dithiothreitol; EAAC1; excitatory amino acid carrier 1; EBSS; Earle's balanced salt solution; EAAT1-2-3; excitatory amino acid transporter 1-2-3; FBS;
IL-10 inhibits the starvation induced autophagy in macrophages via class I phosphatidylinositol 3-kinase (PI3K) pathway
Keywords: EBSS; Earle's balanced salts solution; EGFP.LC3; EGFP fusion LC3B protein; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; HIV-1; human immunodeficiency virus-1; mTORC; mammalian target of rapamycin complex; PI3K; phosphatidylinositol 3-kinase; Th; T hel
Pineal melatonin synthesis is altered in Period1 deficient mice
Keywords: Aanat; circadian; amplitude modulation; negative regulator complex; Aanat; arylalkylamine-N-acetyltransferase; Arp; acidic ribosomal phosphoprotein; Bmal1; brain and muscle Arnt-like protein1; Clock; circadian locomotor output cycles; CRE; cAMP-responsive
Schistosoma mansoni: Chemoreception through n-acetyl-d-galactosamine-containing receptors in females offers insight into increased severity of schistosomiasis in individuals with blood group A
Keywords: Blood groups; Chemoattraction; Con A; concanavalin A; EBSS; Earle's balanced salt solution; ES products; excretory-secretory products; Gal; d-galactose; GalNAc; n-acetyl-d-galactosamine; GlcNAc; n-acetyl-d-glucosamine; lectins; MMI; mean migration ind
Activation of GABA receptors attenuates neuronal apoptosis through inhibiting the tyrosine phosphorylation of NR2A by Src after cerebral ischemia and reperfusion
Keywords: cerebral ischemia; GABA receptor; NMDA receptor; muscimol; baclofen; Src; CAMK II; CaM-dependent protein kinase II; DAPI; 4â²,6-diamidino-2-phenylindole dihydrochloride; DMSO; dimethyl sulfoxide; EBSS; Earl's balanced salt solution; h-DMEM; high-glucos
Putative role of heparan sulfate proteoglycan expression and shedding on the proliferation and survival of cells after photodynamic therapy
Keywords: PDT; photodynamic therapy; PS; photosensitizer; ROS; reactive oxygen species; ECM; extracellular matrix; GAG; glycosaminoglycans; PG; proteoglycan; HS; heparan sulfate; DS; dermatan sulfate; CS; chondroitin sulfate; EC; endothelial cell; EJ-ras-EC; endoth
The spermidine synthase of the malaria parasite Plasmodium falciparum: Molecular and biochemical characterisation of the polyamine synthesis enzyme
Keywords: AdoMetDC; S-adenosylmethionine decarboxylase; APA; 1-aminooxy-3-aminopropane; APE; 5-amino-1-pentene; dcAdoMet; decarboxylated S-adenosylmethionine; EBSS; Earle's balanced salt solution; ODC; ornithine decarboxylase; 4MCHA; trans-4-methylcyclohexyl-amine;
Signal transduction pathways leading to increased eIF4E phosphorylation caused by oxidative stress
Keywords: BSO; buthionine sulfoximine; DMEM; Dulbecco's modified essential medium; EBSS; Earle's Balanced Salts Solution; EGF; epidermal growth factor; eIF; eukaryotic initiation factor; eIF4E-BP; eIF4E-binding protein; FBS; fetal bovine serum; GCS; glutathione cys
Hypochlorous acid-mediated mitochondrial dysfunction and apoptosis in human hepatoma HepG2 and human fetal liver cells: role of mitochondrial permeability transition
Keywords: ANT; adenine nucleotide translocase; BKA; bongkrekic acid; CSA; cyclosporin A; CyD; cyclophilin D; ÎΨm; mitochondrial membrane potential; EBSS; Earle's buffered salt solution; GC-MS; gas chromatography-mass spectrometry; GSH; reduced glutathione; HFL;