Mutants of human αB-crystallin cause enhanced protein aggregation and apoptosis in mammalian cells: Influence of co-expression of HspB1

► Mutants of αB-crystallin expression in cells cause aggregates and apoptosis. ► HspB1 co-expression suppresses aggregates in all mutants. ► HspB1 co-expression decreases apoptosis in P20S, D109H, R120G and A171T.