Serum androgen level is determined by autosomal dominant inheritance and regulates sex-related CYP genes in pigs

► The serum androgen level in males is higher in Meishan pigs than Landrace pigs. ► Crossbreeding was performed between Meishan and Landrace pigs. ► Serum androgen level is determined by autosomal dominant inheritance. ► Serum androgen level is not regulated by only one gene. ► Androgen is a host factor for the constitutive expression of hepatic CYPs in pigs.