Effect of diet composition on coenzyme A and its thioester pools in various rat tissues

► Changes in the size and composition of CoA and its thioester pools in rat tissues. ► Changes in the size of total CoA pool in response to the composition of diet. ► Behavior of CoA and its thioesters in the tissues of diet-induced obese rats. ► Decrease of total CoA content in the liver when feeding a high-fat diet.