Yeast hnRNP-related proteins contribute to the maintenance of telomeres

► Yeast hnRNP-related proteins are able to prevent faster senescence in telomerase-null cells. ► The conserved RRMs in Npl3 are important for telomere maintenance. ► Human hnRNP A1 is unable to complement the lack of NPL3 in yeast. ► Npl3 and Cbc2 may work as telomere capping proteins.