Abnormal DNA methylation of ITGAL (CD11a) in CD4+ T cells from infants with biliary atresia

► CD11a expression is significantly decreased in BA CD4+ T cells. ► CD11a promoter region in BA CD4+ T cells is hypermethylation. ► DNA methylation inhibitor decreased CD11a promoter methylation and increased CD11a mRNA in BA CD4+ T cells.