Identification of the phosphorylation sites on intact TRPM7 channels from mammalian cells

► This study is the first MS-based analysis of the phosphorylation sites in intact TRPM7. ► We identified 14 phosphorylation sites of intact TRPM7, eight of which have not been previously reported. ► TRPM7 are phosphorylated at multiple sites, which may modulate its activity and functions.