Protective effect of catechin in type I Gaucher disease cells by reducing endoplasmic reticulum stress

► Catechin reduces the expression level of ER stress marker protein in type I Gaucher disease cells. ► Catechin induces the proliferation rate of GD cells similar levels to normal cells. ► Catechin improves wound healing activity. ► Catechin-mediated reductions in ER stress may be associated with enhanced cell survival. ► We identified catechin as a protective agent against ER stress in GD cells.