The GTPase TcRjl of the human pathogen Trypanosoma cruzi is involved in the cell growth and differentiation

► TcRjl is a Ras-related GTPase described in Trypanosoma cruzi. ► TcRjl is mainly found in the GTP-bound state in T. cruzi. ► TcRjl is localized closed to the flagellar apparatus. ► TcRjl function is required for cell growth. ► TcRjl overexpression blocks T. cruzi metacyclogenesis.