LC8 dynein light chain (DYNLL1) binds to the C-terminal domain of ATM-interacting protein (ATMIN/ASCIZ) and regulates its subcellular localization

► We have screened a human library with dynein light chain DYNLL1 (DLC8) as bait. ► Dynein light chain DYNLL1 binds to ATM-kinase interacting protein (ATMIN). ► ATMIN has 17 SQ/TQ motifs, a motif frequently found in DYNLL1-binding partners. ► The two proteins interact in vitro, with ATMIN displaying at least five binding sites. ► The interaction of ATMIN and DYNNL1 in transfected cells can also be observed.