Constitutive stabilization of ß-catenin in the dental mesenchyme leads to excessive dentin and cementum formation

► Stabilization of ß-catenin leads to excessive formation of dentin and cementum. ► Wnt/ß-catenin signaling regulates differentiation of odontoblast and cementoblast. ► Wnt/ß-catenin signaling also regulates matrix formation of dentin and cementum.