Krüppel-like factor-10 is directly regulated by carbohydrate response element-binding protein in rat primary hepatocytes

► ChREBP directly regulates rat Klf-10 gene expression. ► KLF-10 partly inhibits glucose induction of ChREBP target genes expression. ► Crosstalk between ChREBP and KLF-10 is involved in the regulation of lipogenic pathway.