High fat diet induced downregulation of microRNA-467b increased lipoprotein lipase in hepatic steatosis

► MicroRNA-467b (miR-467b) is downregulated in high fat diet induced hepatic steatosis. ► Lipoprotein lipase is a direct target of miR-467b. ► MiR-467b - lipoprotein lipase pathway is involved in the insulin resistance of hepatocytes.