Conjugated linoleic acid in the maternal diet differentially enhances growth and cortical spreading depression in the rat progeny

► We explored brain effects of dietary conjugated linoleic acid (CLA), in rats. ► We recorded cortical spreading depression (CSD) and measure its propagation velocity. ► We describe a CSD-facilitation by CLA dietary treatment, compared to CLA-free rats. ► Data are medically relevant as CSD is related to diseases like migraine and epilepsy.