Aminoacylase 1-catalysed deacetylation of bioactives epoxides mycotoxin-derived mercapturates; 3,4-epoxyprecocenes as models of cytotoxic epoxides

► First study of acylase 1 role in toxicity of bioactive epoxides from aflatoxin B1. ► Specific mercapturated substrates have been synthesised. ► Catalytic activity was discussed in a structure-function relationship.