کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10825659 1064662 2014 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Assembly of chemically modified G-rich sequences into tetramolecular DNA G-quadruplexes and higher order structures
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Assembly of chemically modified G-rich sequences into tetramolecular DNA G-quadruplexes and higher order structures
چکیده انگلیسی
In this review, we introduce the biophysical and biochemical methods currently used to investigate the structures and stabilities of tetramolecular DNA G-quadruplexes containing chemical modifications. We hope this paper will guide others as they perform similar experiments leading to more information about the effects of chemical modifications on G-quadruplex formation. The structures of tetramolecular quadruplexes and some higher order structures based on tetramolecular quadruplexes are also described.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Methods - Volume 67, Issue 2, 15 May 2014, Pages 159-168
نویسندگان
, , , , , ,