کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10826438 | 1064762 | 2007 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Bioinformatics approaches to quadruplex sequence location
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شیمی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Bioinformatics approaches to quadruplex sequence location Bioinformatics approaches to quadruplex sequence location](/preview/png/10826438.png)
چکیده انگلیسی
Guanine quadruplex structures are potentially useful therapeutic targets. There have been several studies attempting to locate genomic sequences which are capable of forming these structures. Since the number of potential quadruplex forming sequences which have been identified is so high, several different strategies have been applied to try and determine which of these sequences may be physiologically relevant and which sequences are most likely to form quadruplex structures. These are based on the limited structural information that is currently available and comparative analyses of the location of these sequences with respect to different genomic regions. Sequence information alone is not enough to identify regions of nucleic acid which participate in quadruplex structures, however it is the starting point for quadruplex structure discovery when complemented with further experimentation.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Methods - Volume 43, Issue 4, December 2007, Pages 246-251
Journal: Methods - Volume 43, Issue 4, December 2007, Pages 246-251
نویسندگان
Alan K. Todd,