Analysis of gene mutations in Chinese patients with maple syrup urine disease

► Rogozna quartz latite formed 27.3 ± 0.1-29.5 ± 0.1 Ma ago from hybridized melts. ► Hybridization originated by mixing of dacite calc-alkaline and K to ultra-K melt. ► Prior to hybridization crystallized amphibole, plagioclase, biotite at 5-10 km. ► Phlogopite and disequilibrium textures formed after injection of K to ultra-K melt. ► Pb-Zn-Ag deposits formed synchronous with quartz latite.