Carotid intima-media thickness is increased in patients with mucopolysaccharidoses

► Carotid IMTs of mucopolysaccharidosis patients and matched controls were measured. ► Carotid IMT of mucopolysaccharidosis cohort was significantly greater than controls. ► No correlations seen with carotid IMT and age or duration of treatment. ► Carotid IMT is a viable marker of cardiovascular disease for mucopolysaccharidosis.