Effect of chronic exposure to rimonabant and phytocannabinoids on anxiety-like behavior and saccharin palatability

► Rimonabant, but not THCV, produced an anxiogenic-like response. ► Δ9-THC also produced an anxiogenic-like response. ► Rimonabant suppressed, but Δ9-THC enhanced, saccharin palatability. ► Chronic exposure did not enhance either behavior.